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The Triple Helix
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Gene Therapy Revitalizes Children’s Hearing
Image Credit: [1] Written by: Christopher Perez ‘27 Edited by: Grace Li ‘26 For the first time, children born completely deaf are hearing their parents’ voices without implants or electronic devices. In a landmark clinical trial published in The New England Journal of Medicine, researchers report that a one-time gene therapy, known as DB-OTO, restored natural hearing in children with a rare inherited form of deafness [2]. The results mark extraditing potential in sensory rest
Triple Helix
Feb 214 min read


New Treatment Exploring CAR-NK Cell Therapy for Triple-Negative Breast Cancer
Figure 1: Immunotherapy where multiple cells are targeting and killing a tumor cell (1) Written by: Lakshmi Vemula ‘29 Edited by: Joanna Sohn ‘28 Imagine your own body turning against you, slowly taking over every organ until it’s too late to stop the spread. The leading cause of death worldwide is cancer, which occurs when normal cells have genetic mutations that lead to tumor cells with uncontrolled growth, disrupting key body functions (2) . One of the most common cancers
Triple Helix
Feb 214 min read


Can’t Lucid Dream? New Hand Glove Designed by MIT Now Enables Dream Control
Figure 1: Dormio glove with sensors that track the user’s sleep [1] Written by: Lakshmi Vemula ’29 Edited by: Joanna Sohn ’28 Whether it’s fighting against ten thousand zombies or having godly water powers like Percy Jackson, dreams have endless possibilities. Some people have the ability to control their dreams, crafting their own special universe without bounds. This is known as lucid dreaming, which is when the dreamer is aware that they are dreaming, and only 21% of the p
Triple Helix
Feb 213 min read


The TLR2-MyD88 Pathway in Alzheimer’s Disease: Linking Innate Immunity to Neurodegeneration
Image Credit: [1] Writer: Ivan Yu ‘29 Editor: Elise Park ‘28 Alzheimer’s Disease (AD) is a neurodegenerative disorder that is characterized by cognitive decline and memory loss, impacting portions of the elderly and of middle-aged adults. While classical models of AD pathogenesis have centered around amyloid-beta (Aβ) accumulation and tau pathology, increasing studies have highlighted the central role of neuroinflammation within disease progression. More specifically, microgl
Triple Helix
Feb 213 min read


A.I. In Medicine: Friend or Foe?
Image Credit: [1] Written by: Pratham Rao ‘27 Edited by: Grace Li ‘26 “What do I do to help me stop my depression?” I’m really sorry you’re feeling this way. Depression can be heavy and isolating, but there are steps you can take to start feeling better. Here’s a roadmap that many people find helpful: Depression is not a personal weakness — it’s a medical condition that can get better with treatment and support. You don’t have to solve it all at once; even small steps count.
Triple Helix
Feb 214 min read


Are You Really Your Age?
Image Credit: [1] Written by: Christopher Perez ‘27 Edited by: Grace Li ‘26 Aging is something we all share. We can mark the passage of time with a calendar, yet the amount of time that has passed since your birth—your chronological age— may not match the age of your body. That deeper measure is called biological age, and it offers a more meaningful glimpse into your health and disease risk. Biological age reflects how our cells and tissues function at a molecular level. Two
Triple Helix
Feb 214 min read


Healthcare Equity for Latinx Communities
Image Citation: [1] Author: Shreya Karthik, ‘29 Editor: Thomas Wang ‘26 Introduction Latinx are the largest minority group in the US, making up 18-19% of the total population [2, 3]. Despite their significant presence, Latinx communities remain severely underrepresented and underserved in healthcare. In 2022, only 6% of US physicians identified as Hispanic in comparison to 56.5% identifying as White and 18.8% as Asian [2, 4]. Numerous studies have demonstrated that Latinx pa
Triple Helix
Feb 214 min read


Eye-Opening Insights into Neural Degeneration in Glaucoma
Image Citation: [1] Written by: Nhi Nguyen ‘28 Edited by: Rocky Mattos-Canedo ‘26 Consider this: of your five senses, which one would you least want to lose? While sensory loss of any variety can adversely impact daily life, most individuals report that losing their sense of sight would be the most devastating (2) . The eyes, being the gateway to the visual system, connect human perception to the surrounding optical environment. However, this system is quite delicate—over 24
Triple Helix
Feb 215 min read


Rise and Shine: How Noise Pollution Hijacks Your Sleep
Image Citation: [1] Written by: Nhi Nguyen ‘28 Edited by: Kevin Pham ‘28 It’s 5 a.m. The sun has barely crested the horizon, yet the hum of traffic—a trash truck rumbling by, motorcycles at untimely hours, wails of an ambulance—still leaks through the closed windows. You stir in your bed, unwilling to wake up. Nevertheless, the slight noise disturbance has already roused the brain from its stages of deep sleep. What should have been a restorative night’s rest has instead trig
Triple Helix
Feb 214 min read


Panda-potent!
Image Credit: [1] Written by Wonjong Ko ‘28 Edited by Alicia Kim ‘28 Pandas are one of the most influential animals, serving as both a global icon and the national treasure of China. With their black and white fur coats and their large, clumsy demeanors, they have gained worldwide fame and adoration. They are gentle, solitary, and slow-moving. These exact traits unfortunately make them vulnerable, as they lack the proper survival skills to protect themselves from human defore
Triple Helix
Feb 214 min read


From Brain Networks to Behavior: Using Functional Connectivity to Understand Autism Spectrum Disorder
Image Citation: [1] By Shreya Karthik ‘29 Edited by Thomas Wang ‘26 It is estimated that 1 in every 88 children experiences some form of Autism Spectrum Disorder (ASD), with a prevalence of about 1% globally [2, 3, 4]. ASD is a group of neurodevelopmental disorders broadly characterized by deficits in social behavior, a pattern of restrictive and repetitive behaviors [5, 6, 7], and difficulties processing sensory stimuli [8, 9, 10]. The impact of an ASD diagnosis is substan
Triple Helix
Feb 216 min read


Organ-on-chip technology
Image Citation: [1] Written by: Annabel Ovonlen ‘29 Edited by: Gloria Yao ‘28 For the longest time, scientists have made a habit of investigating diseases and biological functions using cell lines or animal models like mice to provide an organismal perspective before initiating any human trials. In recent years, advances in stem cell biology birthed organoids: stem-cell derived mini 3D tissue cultures that resemble an organ. Recently, with the help of biomedical engineers, th
Triple Helix
Feb 215 min read


The Shape of Life: Protein Modeling, Quantum Chemistry, and a Nobel Prize
Image Citation: [1] Writer: Huyen Nguyen ‘28 Editor: Morgan Rafferty ‘28 When you think about life’s machinery—digesting food, fighting infections, even allowing neurons to fire—all of these processes rely on proteins. These molecules fold into intricate three-dimensional shapes that dictate what they can do, much like how a key’s grooves determine which locks it can open. Predicting those shapes has been one of biology’s grand challenges for decades. In 2024, the Nobel Pri
Triple Helix
Feb 215 min read


Mini But Mighty: How Microbes In The Uterine and Endometrial Microbiome Are Causing Endometriosis
Image Citation: [1] Writer: Annabel Ovonlen ‘29 Editor: Morgan Rafferty ‘28 Bacteria. They’re everywhere from our scalps to the gut and even our lungs. In the various regions of our bodies, these microbes form powerful yet invisible colonies and kingdoms known as microbiomes. For women, the state of the uterine microbiome is particularly important because it affects other aspects of health. For the longest time, scientists have focused their efforts on understanding the compo
Triple Helix
Feb 215 min read


AI: Your Manuscript’s New Co-Author?
Image Citation: [1] Written by Alexandra Bergholt ‘27 Edited by Andrew Ni ‘26 Imagine walking into a prestigious scientific conference. You expect the familiar buzz of research you know so well, hundreds of researchers debating their findings, poster sessions stretching across the room, excited conversations between scientists exchanging ideas spilling out of lecture halls. What if, however, this noise is replaced by the thrum of machines? What if the researchers, presenters
Triple Helix
Feb 216 min read


Ticking Within, the Molecular Clock of Aging
Image Citation: [1] Written by Karon Johnson ‘27 Edited by Andrew Ni ‘26 Within every cell of our body, a metronome keeps time, not in seconds or years, but in molecular marks. These markers of time, called epigenetic clocks, measure the passage of biological time. Unlike normal clocks, which tick consistently with gears and sound, our epigenetic clocks measure time through tiny chemical marks that collect on our DNA; they speed up, stall, and sometimes even rewind, influen
Triple Helix
Feb 214 min read


The Nitroplast: A New Organelle on the Block
Figure 1: The nitroplast organelle located in the B. bigelowii bacterium [1] Written by Karon Johnson ‘27 Edited by Andrew Ni ‘26 Remember that one phrase we all repeated in middle school biology, almost like a chant? “The mitochondria is the powerhouse of the cell.” It was simple, catchy, and let’s be honest, probably the only thing most of us took away from the class. But behind that phrase lies a world of intricate cellular machinery. In the world of biology, organell
Triple Helix
Feb 214 min read


Genetically Engineering Immune Cells: The Future of CAR-T Cell Therapy
Image Citation: [1] Writer: Augusto Castaner ’29 Editor: Yumiko Imai ’26 Imagine your body’s immune cells are like a security force, and cancer cells are intruders that infiltrate your neighborhood block (body) and break into your home (an organ) wearing convincing disguises. For decades, these invaders were fought back with blunt force—chemotherapy and radiation—that damaged not only your house, but also the entire neighborhood (surrounding cells and tissues) and security fo
Triple Helix
Feb 214 min read


A Science Experiment in Your Own Backyard – Factors Affecting Diverse Hydrangea Colors
Figure 1: Variation in hydrangea colors (1) . Written by: Ava Gell, ’28 Edited by: Yumiko Imai, ‘26 Take a walk around any green space in New England, and you’re sure to stumble across one of nature’s most beautiful science experiments – the hydrangea. They range in size from a small shrub to an eight-foot-tall tree to a lush climbing vine (2) . They are perhaps best known for their magical pastel hues, which range from pink to blue. The cause of this range of color is its ow
Triple Helix
Feb 215 min read


Could Vitamin D Help Us Age Better?
Recent Study Says… Maybe Image Caption: [1] Written by: Max Mislow ‘28 Edited by: Allison Shea ‘28 How can we slow down the aging process? This challenging question has been at the forefront of scientific research for centuries. Between genetic factors, lifestyle choices, or even the environment one lives in, there are a multitude of things to consider when discussing what contributes to cellular aging [2]. To address this, scientists from all different backgrounds have been
Triple Helix
Feb 34 min read
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